Alcohol and illicit drugs: a cohort among tuberculosis cases

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DOI:

https://doi.org/10.21727/rpu.v16i3.5551

Abstract

Introduction: Tuberculosis (TB) is an ancient disease that persists as a health problem. Objective: to investigate the influence of alcohol and illicit drug use on the clinical evolution of TB cases in Rondônia. Materials and method: observational, analytical, retrospective cohort study with a quantitative approach, based on TB case records in the Rondônia Notifiable Diseases Information System, from 2018 to 2022. Sociodemographic, clinical, and follow-up data were analyzed in Microsoft Excel to calculate the incidence and mortality coefficients with graphical representation, as well as through descriptive statistics, relative risk with their respective 95% confidence intervals, considering p<0.05, in the Statistica software, TIBCO, version 13.5.0.17, after meeting ethical precepts. Results and discussion: 224 illicit drug users and 290 alcoholics were selected. There was a significant increase in the risk among users of illicit drugs for the prison population, lack of knowledge about the presence of another disease or associated condition, living in a rural area, reentry after abandonment, failure to perform sputum smear microscopy, chest X-ray and DOT, 11 or more contacts identified and examined. Alcoholic individuals showed risk with diabetes mellitus, extrapulmonary or mixed form, failure to perform or blank for the TRM-TB, secondary and tertiary care as the reporting unit and secondary care as the care unit. Conclusion: the use of substances showed associations with the clinical evolution of individuals with TB who perpetuate the chain of transmission of the disease.

Keywords: Tuberculosis; Alcoholism; Illicit drugs.

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Author Biographies

Mariana Bobato Pulgatti, Universidade Federal de Rondônia (UNIR)

Discente (Gradução em Medicina) Universidade Federal de Rondônia - UNIR, Porto Velho, Rondônia, Brasil. 

Arlindo Gonzaga Branco Júnior, Universidade Federal de Rondônia (UNIR)

Docente do Curso de Medicina da Universiade Federal de Rondônica – UNIR, Porto Velho, Rondônia, Brasil. 

Nathalia Halax Orfão, Universidade Federal de Rondônia (UNIR)

Docente do Curso de Medicina da Universiade Federal de Rondônica – UNIR, Porto Velho, Rondônia, Brasil. 

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Published

2025-10-31

Issue

Vol. 16 No. 3 (2025): Revista Pró-UniverSUS V 16 N 3

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Articles

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Copyright (c) 2025 Mariana Bobato Pulgatti, Arlindo Gonzaga Branco Júnior, Nathalia Halax Orfão

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